I'm part of that email chain that I know a fair amount of people on this website know about.
Every time there's a new one someone complains about wanting to be taken off. I understand their point of view. I really am sympathetic, however I also understand that not everyone has the time to go through and filter out everyone who doesn't want to be part of it anymore.
So here is my counterpoint. Filters exist.
These people bring up that they've been feeling spammed for years and I get that. I would be aggravated in their shoes as well, but at the same time if the problem isn't being fixed by the people on the other end, then it kind of seems like setting up a filter would fix it all the same?
Filtering out emails that contain words like request, rp, roleplay would probably be a decent start.